parosteal osteosarcoma mimicking osteochondroma a radio-histologic approach on two casesparosteal骨肉瘤模仿骨软骨瘤radio-histologic方法在两种情况.pdfVIP

CLINICAL SARCOMA RESEARCH Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases Papathanassiou et al. Papathanassiou et al. Clinical Sarcoma Research 2011, 1:2 /content/1/1/2 (25 July 2011) Papathanassiou et al. Clinical Sarcoma Research 2011, 1:2 /content/1/1/2 CLINICAL SARCOMA RESEARCH RESEARCH Open Access Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases 1 2 3 2 4 Zafiria G Papathanassiou , Marco Alberghini , Philippe Thiesse , Marco Gambarotti , Giuseppe Bianchi , Cristina Tranfaglia5 and Daniel Vanel1* Abstract Objective: Parosteal osteosarcoma is a well-differentiated variant of osteosarcoma that affects the surface of the bone. The imaging pattern is very typical. We report two cases mimicking an osteochondroma, radiologically and histologically and propose an explanation. Material: The review of 86 parosteal osteosarcomas of bone revealed this atypical pattern only once. A consultation case was received in the same time, and added to ours. Patients were 28 years old and 56 years old females. Imaging studies included two radiographs, two CTscans, one MRI examination and one bone scan and the results were compared to histology. Results: On imaging, both lesions presented as ossified lobulated masses attached with a broad base to the underlying cortex. No radiolucent cleft separated the masses and the host bone and cortex continuity between the mass and the femur was seen, with medullary communication. The marrow of the mass had a different density a