peanut allergy an overview花生过敏概述.pdfVIP

Original article Peanut Allergy: An Overview Nasser Al-Ahmed, MD, Shirina Alsowaidi, MD, and Peter Vadas, MD, PhD Peanut allergies have been increasing in prevalence in most industrialized countries. Onset is typically in early childhood, with a trend towards earlier ages of presentation. the allergy is lifelong in most affected children, although 15–22% will outgrow their peanut allergy, usually before their teenage years. Manifestations of peanut allergy range from mild to severe, and risk factors predisposing to severe reactions are discussed. However, even in the absence of risk factors, peanut allergic individuals may still experience life-threatening anaphylactic reactions. approaches to investigation and treatment, patterns of cross-reactivity and possible causes of rising prevalence are discussed. Key words: peanut, allergy, anaphylaxis, nuts ood allergy is a common problem encountered by pri- challenges, the total estimate for clinical peanut allergy was Fmary care physicians. It is estimated to afect 4 to 8% of 1.5% of 3- to 4-year-old children.10 The results from those two children and 1 to 2% of adults and is considered a major cause studies are suggestive of an overall increase in the prevalence of life-threatening hypersensitivity reactions.1–3 Eight foods are of peanut allergy among children. Another study estimated responsible for more than 90% of food allergies: cow’s milk, the prevalence of peanut allergy to be 1.34% among primary 4 egg, soy, wheat, peanut, tree nuts, ish, and shellish. Among school children in a Canadian province.11 those foods, peanut has attracted considerable attention for several reasons. Peanut allergy is common, typically with on- Clini