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physiologically-based testing system for the mechanical characterization of prosthetic vein valves有着生理基础的机械特性测试系统的假体静脉瓣膜.pdf

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physiologically-based testing system for the mechanical characterization of prosthetic vein valves有着生理基础的机械特性测试系统的假体静脉瓣膜

BioMedical Engineering OnLine BioMed Central Research Open Access Physiologically-based testing system for the mechanical characterization of prosthetic vein valves Stanley E Rittgers*, Matt T Oberdier and Sharath Pottala Address: Department of Biomedical Engineering, The University of Akron, Akron, OH 44325, USA Email: Stanley E Rittgers* - srittgers@; Matt T Oberdier - oberdiermt@; Sharath Pottala - sharat_chand@ * Corresponding author Published: 13 July 2007 Received: 8 March 2007 Accepted: 13 July 2007 BioMedical Engineering OnLine 2007, 6:29 doi:10.1186/1475-925X-6-29 This article is available from: /content/6/1/29 © 2007 Rittgers et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Due to the relatively limited amount of work done to date on developing prosthetic vein (as opposed to cardiac) valves, advances in this topic require progress in three distinct areas: 1) improved device design, 2) relevant device testing conditions, and, 3) appropriate parameters for evaluation of results. It is the purpose of this paper to address two of these issues (#2 and #3) by: 1) performing a study of normal volunteers to quantify the anatomy and hemodynamic features of healthy venous valves, 2) construct