pitfalls in efficacy testing – how important is the validation of neutralization of chlorhexidine digluconate陷阱功效测试u2014u2014重要的是如何验证的中和洗必泰digluconate.pdfVIP
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pitfalls in efficacy testing – how important is the validation of neutralization of chlorhexidine digluconate陷阱功效测试u2014u2014重要的是如何验证的中和洗必泰digluconate
Annals of Clinical Microbiology and
Antimicrobials BioMed Central
Research Open Access
Pitfalls in efficacy testing – how important is the validation of
neutralization of chlorhexidine digluconate?
1,2 2 1,3
Mirja Reichel* , Peter Heisig and Günter Kampf
Address: 1Bode Chemie GmbH Co, KG, Scientific Affairs, Melanchthonstr. 27, 22525, Hamburg, Germany, 2Department of Pharmaceutical
Biology and Microbiology, Institute of Pharmacy, University of Hamburg, Hamburg, Germany and 3Institute for Hygiene and Environmental
Medicine, Ernst Moritz Arndt University, Walther-Rathenau-Str. 49a, 17475, Greifswald, Germany
Email: Mirja Reichel* - mirja.reichel@bode-chemie.de; Peter Heisig - heisig@chemie.uni-hamburg.de; Günter Kampf - guenter.kampf@bode-
chemie.de
* Corresponding author
Published: 2 December 2008 Received: 28 August 2008
Accepted: 2 December 2008
Annals of Clinical Microbiology and Antimicrobials 2008, 7:20 doi:10.1186/1476-0711-7-20
This article is available from: /content/7/1/20
© 2008 Reichel et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Effective neutralization of active agents is essential to obtain valid efficacy results,
especially w
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