plasmonic nanostructures for nano-scale bio-sensing电浆纳米bio-sensing纳米结构.pdfVIP

Sensors 2011, 11, 10907-10929; doi:10.3390/s111110907 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Review Plasmonic Nanostructures for Nano-Scale Bio-Sensing Taerin Chung 1, Seung-Yeol Lee 1, Eui Young Song 1, Honggu Chun 2 and Byoungho Lee 1,* 1 National Creative Research Center for Active Plasmonics Application Systems, Inter-University Semiconductor Research Center and School of Electrical Engineering, Seoul National University, Gwanak-Gu Gwanakro 1, Seoul 151-744, Korea; E-Mails: taerinc@ (T.C.); ssodra87@snu.ac.kr (S.-Y.L.); song9758@snu.ac.kr (E.Y.S.) 2 Department of Biomedical Engineering, Korea University, Seoul 136-701, Korea; E-Mail: bioneer@ * Author to whom correspondence should be addressed; E-Mail: byoungho@snu.ac.kr; Tel.: +82-2-880-7245; Fax: +82-2-873-9953. Received: 8 October 2011; in revised form: 13 November 2011 / Accepted: 14 November 2011 / Published: 21 November 2011 Abstract: The optical properties of various nanostructures have been widely adopted for biological detection, from DNA sequencing to nano-scale single molecule biological function measurements. In particular, by employing localized surface plasmon resonance (LSPR), we can expect distinguished sensing performance with high sensitivity and resolution. This indicates that nano-scale detections can be realized by using the shift of resonance wavelength of LSPR in response to the refractive index change. In this paper, we overview various plasmonic nanostr