polymorphisms in il12a and cockroach allergy in children with asthma多态性在il12a和蟑螂过敏与哮喘儿童.pdf

Clinical and Molecular Allergy BioMed Central Research Open Access Polymorphisms in IL12A and cockroach allergy in children with asthma 1,3,4 1,2,4 5 Michael Pistiner , Gary M Hunninghake , Manuel E Soto-Quiros , 5 1,4,6 1,4,6 1 Lydiana Avila , Amy Murphy , Jessica Lasky-Su , Brooke Schuemann , Barbara J Klanderman1,4, Benjamin A Raby1,2,4 and Juan C Celedón* 1,2,4 Address: 1Channing Laboratory, Department of Medicine, Brigham and Womens Hospital, Boston, MA, USA, 2Division of Pulmonary/Critical Care Medicine, Department of Medicine, Brigham and Womens Hospital, Boston, MA, USA, 3Division of Immunology, Childrens Hospital, Boston, MA, USA, 4Harvard Medical School, Boston, MA, USA, 5Division of Pediatric Pulmonology, Hospital Nacional de Niños, San José, Costa Rica and 6Dept. of Biostatistics, Harvard School of Public Health, Boston, MA, USA Email: Michael Pistiner - Michael.Pistiner@; Gary M Hunninghake - ghunninghake@; Manuel E Soto- Quiros - msotoq@hnn.sa.cr; Lydiana Avila - lydiana98@; Amy Murphy - amy.murphy@; Jessica Lasky- Su - jessica.su@; Brooke Schuemann - brooke.schuemann@; Barbara J Klanderman - rebjk@; Benjamin A Raby - benjamin.raby@; Juan C Celedón* - juan.celedon@ * Corresponding author Published: 31 July 2008 Received: 17 June 2008 Accepted: 31 Ju