predicting a low cortisol response to adrenocorticotrophic hormone in the critically ill a retrospective cohort study促肾上腺皮质的预测低皮质醇反应激素在危重回顾性队列研究.pdf

Available online /content/11/3/R61 Vol 11 No 3 Open Access Research Predicting a low cortisol response to adrenocorticotrophic hormone in the critically ill: a retrospective cohort study 1 1 1 1 Margriet FC de Jong , Albertus Beishuizen , Jan-Jaap Spijkstra , Armand RJ Girbes , Rob JM 1 2 1 Strack van Schijndel , Jos WR Twisk and AB Johan Groeneveld 1Department of Intensive Care, Institute for Cardiovascular Research, Vrije Universiteit Medical Center, De Boelelaan, 1081 HV Amsterdam, The Netherlands 2Department of Epidemiology and Biostatistics, Institute for Cardiovascular Research, Vrije Universiteit Medical Center, De Boelelaan, 1081 HV Amsterdam, The Netherlands Corresponding author: AB Johan Groeneveld, johan.groeneveld@vumc.nl Received: 3 Apr 2007 Revisions requested: 21 Apr 2007 Revisions received: 30 Apr 2007 Accepted: 24 May 2007 Published: 24 May 2007 Critical Care 2007, 11:R61 (doi:10.1186/cc5928) This article is online at: /content/11/3/R61 © 2007 de Jong et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Identification of risk factors for diminished cortisol low platelets, low pH and bicarbonate, low albumin levels, high response to adrenocorticotrophic hormone (ACTH) in the Sequential Organ