prevalence rate, predictors and long-term course of probable posttraumatic stress disorder after major trauma a prospective cohort study流行率、预测和长期重大创伤后可能的创伤后应激障碍的前瞻性群组研究.pdfVIP

Haagsma et al. BMC Psychiatry 2012, 12:236 /1471-244X/12/236 RESEARCH ARTICLE Open Access Prevalence rate, predictors and long-term course of probable posttraumatic stress disorder after major trauma: a prospective cohort study 1* 2,4 2 1 2 Juanita A Haagsma , Akkie N Ringburg , Esther MM van Lieshout , Ed F van Beeck , Peter Patka , Inger B Schipper3 and Suzanne Polinder1 Abstract Background: Among trauma patients relatively high prevalence rates of posttraumatic stress disorder (PTSD) have been found. To identify opportunities for prevention and early treatment, predictors and course of PTSD need to be investigated. Long-term follow-up studies of injury patients may help gain more insight into the course of PTSD and subgroups at risk for PTSD. The aim of our long-term prospective cohort study was to assess the prevalence rate and predictors, including pre-hospital trauma care (assistance of physician staffed Emergency Medical Services (EMS) at the scene of the accident), of probable PTSD in a sample of major trauma patients at one and two years after injury. The second aim was to assess the long-term course of probable PTSD following injury. Methods: A prospective cohort study was conducted of 332 major trauma patients with an Injury Severity Score (ISS) of 16 or higher. We used data from the hospital trauma registry and self-assessment surveys that included the Impact of Event Scale (IES) to measure probable PTSD symptoms. An IES-score of 35 or higher was used as indication for the presence of probable PTSD. Results: One year after injury measurements of 226 major trauma patients were obtained (response rate 68%). Of these patients 23% had an IES-score of 35 or higher, indicating probable PT