probability of ventricular fibrillation allometric model based on the st deviation心室纤维性颤动的概率异速生长的模型基于st偏移.pdfVIP
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probability of ventricular fibrillation allometric model based on the st deviation心室纤维性颤动的概率异速生长的模型基于st偏移
Bonomini et al. BioMedical Engineering OnLine 2011, 10:2
/content/10/1/2
RESEARCH Open Access
Probability of ventricular fibrillation: allometric
model based on the ST deviation
1 1,2 1*
Maria P Bonomini , Pedro D Arini , Max E Valentinuzzi
* Correspondence: Abstract
maxvalentinuzzi@.ar
1Instituto de Ingeniería Biomédica Background: Allometry, in general biology, measures the relative growth of a part in
(IIBM), Facultad de Ingeniería (FI),
Universidad de Buenos Aires (UBA), relation to the whole living organism. Using reported clinical data, we apply this
Buenos Aires, Argentina. concept for evaluating the probability of ventricular fibrillation based on the
electrocardiographic ST-segment deviation values.
Methods: Data collected by previous reports were used to fit an allometric model in
order to estimate ventricular fibrillation probability. Patients presenting either with
death, myocardial infarction or unstable angina were included to calculate such
probability as, VFp = δ + b (ST), for three different ST deviations. The coefficients δ
and b were obtained as the best fit to the clinical data extended over observational
periods of 1, 6, 12 and 48 months from occurrence of the first reported chest pain
accompanied by ST deviation.
Results: By application of the above equation in log-log representation, the fitting
procedure
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