原创力文档proliferation and differentiation potential of chondrocytes from osteoarthritic patients软骨细胞的增殖和分化潜力的骨关节炎的患者.pdfVIP
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proliferation and differentiation potential of chondrocytes from osteoarthritic patients软骨细胞的增殖和分化潜力的骨关节炎的患者
Available online /content/7/3/R560
Vol 7 No 3 Open Access
Research article
Proliferation and differentiation potential of chondrocytes from
osteoarthritic patients
1 1 1 1
Tommi Tallheden , Catherine Bengtsson , Camilla Brantsing , Eva Sjögren-Jansson ,
2 2 2 1
Lars Carlsson , Lars Peterson , Mats Brittberg and Anders Lindahl
1Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
2Department Orthopaedics, Sahlgrenska University Hospital, Gothenburg, Sweden
Corresponding author: Tommi Tallheden, tommi.tallheden@medic.gu.se
Received: 6 Sep 2004 Revisions requested: 18 Oct 2004 Revisions received: 30 Dec 2004 Accepted: 3 Jan 2005 Published: 3 Mar 2005
Arthritis Research Therapy 2005, 7:R560-R568 (DOI 10.1186/ar1709)
This article is online at: /content/7/3/R560
© 2005 Tallheden et al.; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/
2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Autologous chondrocyte transplantation (ACT) has been proliferation potential and are able to redifferentiate in a three-
shown, in long-term follow-up studies, to be a promising dimensional pellet model. During the redifferentiation, the OA
treatment for the repair of isolated cartilage lesions. The method cells expressed increasing amou
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