pulmonary metastasis of a papillary thyroidcarcinoma and primary lung adenocarcinoma twocoincident carcinomas at the same location肺转移的乳头状thyroidcarcinoma和主肺腺癌twocoincident癌在同一位置.pdfVIP

Xue et al. Diagnostic Pathology 2013, 8:26 /content/8/1/26 CASE REPORT Open Access Pulmonary metastasis of a papillary thyroid carcinoma and primary lung adenocarcinoma: two coincident carcinomas at the same location 1† 1,2† 3 1 4 3,4 1* 1* Liyan Xue , Zhonghua Luan , Ying Liu , Shuangmei Zou , Jun Jiang , Ning Wu , Ning Lu and Dongmei Lin Abstract Tumor-to-tumor metastasis is a fairly rare phenomenon. The lung cancers are the most common donors, but are exceedingly rare as recipients. Here we report a case of a lung adenocarcinoma acting as the recipient of papillary thyroid carcinoma, with multiple spreading foci of the two cancers in the lung simultaneously. The morphology and immunohistochemisty (Napsin-A, Thyroglobulin) are very important in differential diagnosis of lung primary adenocarcinoma and metastatic papillary thyroid carcinoma. Virtual Slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/ vs/2069496615891134 Keywords: Tumor-to-tumor metastasis, Papillary thyroid carcinoma, Lung adenocarcinoma, Napsin-A, Thyroglobulin Background Case presentation Coexistence of two or more primary neoplasms in one A 65-year-old Chinese man underwent total thyroidectomy patient is not uncommon, however, tumor-to-tumor and bilateral neck dissection with 131I treatment after metastasis is a fairly uncommon but interesting phe- that for papillary thryoid cancer in a local hospital. The nomenon. The most frequent recipient is renal clear papillary thryoid cancer extended to per