原创力文档regulation of platelet-leukocyte interaction in simulated ecc attenuation with heparin surface modification监管platelet-leukocyte互动模拟ecc衰减与肝素表面改性.pdfVIP
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regulation of platelet-leukocyte interaction in simulated ecc attenuation with heparin surface modification监管platelet-leukocyte互动模拟ecc衰减与肝素表面改性
Abstracts International Symposium on the Pathophysiology of CPB P1
Abstracts of the International Symposium on the
Pathophysiology of Cardiopulmonary Bypass
Aachen, December 12 1998
1 Effects of blood viscosity on renal function during cardiopulmonary bypass — investigations in infants and
experimental setting in pig kidneys
1 1 1 2 1 1 1
S Dittrich , M Priesemann , A Schuth , C Müller , T Fischer , V Alexi-Meskishvili and PE Lang
1Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, Germany, and 2Departement of Clinical Chemistry and Biochemistry, Charité,
Humboldt University, Berlin
OObbjjeeccttiivveess:: Acute renal failure (ARF) is a common complication indicating moderate glomerular and tubular damage. During AT,
following open heart surgery especially in infants. Effects of blood blood was hemodiluted to a hemoglobin of 8.4 ± 0.4 g/dl. Thus,
viscosity on renal function are well known, but have not been blood viscosity during AT and hypothermia was slightly below
investigated in cardiopulmonary bypass (CPS) as yet. pre-CPB values. Lower blood viscosity was related to less renal
damage (P 0.01).
MMaatteerriiaall aanndd mmeetthhooddss:: We investigated blood viscosity and differ-
ent markers of glomerular and tubular renal function in a group of In isolated pig-kidneys, group I (n = 14) was perfused with a
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