remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit a randomized, double-blind controlled trial [isrctn43755713]基于remifentanil和芬太尼镇痛镇静病人提供舒适的重症监护室一项随机、双盲对照试验(isrctn43755713).pdfVIP

Available online /content/8/1/R1 Research Open Access Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: a randomized, double-blind controlled trial [ISRCT 1 2 3 4 5 Bernd Muellejans , Angel López , Michael H Cross , César Bonome , Lachlan Morrison and Andrew JT Kirkham6 1Director of Anaesthesiology Intensive Care Medicine, Klinikum Karlsburg, Herz-und Diabeteszentrum Mecklenburg-Vorpommern Klinik für Anaesthesiologie und Intensivmedizin, Karlsburg, Germany 2Consultant Anaesthesiologist, Servicio de Medicina Intensiva, Hospital Universitario Infanta Cristina, Badajoz, Spain 3Consultant Anaesthetist, Department of Anaesthesia, Leeds General Infirmary, Leeds, UK 4Attending Staff, Department of Anaesthesiology, Hospital Juan Canalejo, Servicio de Anestesiologia y Reanimación, La Coruña, Spain 5Consultant in Anaesthetics and Intensive Care, Department of Anaesthesia, St. John’s Hospital, Livingston, UK 6Global Study Manager, GlaxoSmithKline Research and Development, Greenford, UK Correspondence: Bernd Muellejans, dr.muellejans@drguth.de Received: 2 October 2003 Critical Care 2004, 8:R1-R11 (DOI 10.1186/cc2398) Accepted: 16 October 2003 This article is online at /content/8/1/R1 © 2004 Muellejans et al., licensee BioMed Central Ltd Published: 20 November 2003 (Print ISSN 1364-8535; Online