resource utilization in patients with schizophrenia who initiated risperidone long-acting therapy results from the schizophrenia outcomes utilization relapse and clinical evaluation (source)资源利用率在精神分裂症患者发起利培酮长效治疗精神分裂症复发和临床评价结果利用的结果(源).pdfVIP

Crivera et al. BMC Psychiatry 2011, 11:168 /1471-244X/11/168 RESEARCH ARTICLE Open Access Resource utilization in patients with schizophrenia who initiated risperidone long- acting therapy: results from the Schizophrenia Outcomes Utilization Relapse and Clinical Evaluation (SOURCE) Concetta Crivera1*†, Cherilyn DeSouza2†, Chris M Kozma3†, Riad D Dirani4†, Lian Mao5† and Wayne Macfadden4† Abstract Background: Schizophrenia is a chronic mental health disorder associated with increased hospital admissions and excessive utilization of outpatient services and long-term care. This analysis examined health care resource utilization from a 24-month observational study of patients with schizophrenia initiated on risperidone long-acting therapy (RLAT). Methods: Schizophrenia Outcomes Utilization Relapse and Clinical Evaluation (SOURCE) was a 24-month observational study designed to examine real-world treatment outcomes by prospectively following patients with schizophrenia initiated on RLAT. At baseline visit, prior hospitalization and ER visit dates were obtained for the previous 12 months and subsequent hospitalization visit dates were obtained at 3-month visits, if available. The health care resource utilization outcomes measures observed in this analysis were hospitalizations for any reason, psychiatric-related hospitalizations, and emergency room (ER) visits. Incidence density analysis was used to assess pre-event and postevent rates per person-year (PY). Results: The primary medical resource utilization analysis included 435 patients who had a baseline visit, ≥1 postbaseline visits after RLAT initiation, and valid hospitalization dates. The number of hospitalizations and ER visits per PY declined significantly (p .0001) after initiation with RLAT. A 41% decrease (difference of -0.29 hospitalizations per PY [95