selection mechanisms underlying high impact biomedical research - a qualitative analysis and causal model选择机制高影响生物医学研究,定性分析和因果模型.pdfVIP

Selection Mechanisms Underlying High Impact Biomedical Research - A Qualitative Analysis and Causal Model Hilary Zelko1,2, Guilherme Roberto Zammar2,3, Ana Paula Bonilauri Ferreira2,4, Amruta Phadtare2,5, Jatin Shah2,6, Ricardo Pietrobon2,6,7* 1 Department of Surgery, Duke University, Durham, North Carolina, United States of America, 2 Research on Research Group, Duke University, Durham, North Carolina, ´ ´ ´ ´ United States of America, 3 Pontifıcia Universidade Catolica do Parana (PUCPR), Curitiba, Parana, Brazil, 4 University of Joinville (UNIVILLE), Joinville, Brazil, 5 Kalpavriksha Healthcare and Research, Thane, Maharashtra, India, 6 Duke NUS Graduate Medical School, Singapore, Singapore, 7 Duke University, Durham, North Carolina, United States of America Abstract Background: Although scientific innovation has been a long-standing topic of interest for historians, philosophers and cognitive scientists, few studies in biomedical research have examined from researchers’ perspectives how high impact publications are developed and why they are consistently produced by a small group of researchers. Our objective was therefore to interview a group of researchers with a track record of high impact publications to explore what mechanism they believe contribute to the generation of high impact publications. Methodology/Principal Findings: Researchers were located in universities all over the globe and interviews were conducted by phone. All interviews were transcribed using standard qualitative methods. A Grounded Theory approach was used to code each transcript, later aggregating concept and categories into overarching explanation model. The model was then translated into a System Dynamics mathematical model to represent its structu