原创力文档structural, thermoanalytical and molecular modeling studies on n-(3-hydroxypropyl) 3α,12α-dihydroxy-5β-cholan-24-amide and its monohydrates结构,thermoanalytical和分子建模研究n -(3-hydroxypropyl)3α,12α-dihydroxy-5β-cholan-24-amide及其一水.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
structural, thermoanalytical and molecular modeling studies on n-(3-hydroxypropyl) 3α,12α-dihydroxy-5β-cholan-24-amide and its monohydrates结构,thermoanalytical和分子建模研究n -(3-hydroxypropyl)3α,12α-dihydroxy-5β-cholan-24-amide及其一水
Molecules 2007, 12, 2161-2178
molecules
ISSN 1420-3049
© 2007 by MDPI
/molecules
Full Research Paper
Structural, Thermoanalytical and Molecular Modeling Studies
on N-(3-hydroxypropyl) 3α,12α-Dihydroxy-5β-cholan-24-amide
and Its Monohydrates
Arto Valkonen*, Erkki Kolehmainen, Manu Lahtinen, Elina Sievänen, Virpi Noponen,
Minna Tolonen and Reijo Kauppinen
Department of Chemistry, University of Jyväskylä, PO. Box 35, FIN-40014 University of Jyväskylä,
Finland
* Author to whom correspondence should be addressed; E-mail: arto.valkonen@jyu.fi
Received: 17 August 2007; in revised form: 9 September 2007/ Accepted: 12 September 2007 /
Published: 12 September 2007
Abstract: The synthetic method for preparing N-(3-hydroxypropyl) 3α,12α-dihydroxy-5β-
cholan-24-amide can lead to formation of at least three different crystal forms – an
anhydrous compound and two monohydrates. The structural and thermal properties of
these forms have been characterized by 13C-CP/MAS-NMR and IR spectroscopy, thermo-
gravimetry, differential scanning calorimetry and by powder and single crystal x-ray
crystallography. In addition, theoretical 13C-NMR chemical shift calculations were also
performed for the anhydrous compound and for the first monohydrate, starting from single
crystal structures and the structures of these species have now been verified. The first
monohydrate, C H NO · H O, crystallizes in orthorhombic space group P2 2 2 with
您可能关注的文档
- sphingosine kinase 1 mediation of expression of the anaphylatoxin receptor c5l2 dampens the inflammatory response to endotoxin鞘氨醇激酶1中介c5l2过敏毒素受体的表达抑制了内毒素的炎症反应.pdf
- sphingosine-1-phosphate-specific g protein-coupled receptors as novel therapeutic targets for atherosclerosissphingosine-1-phosphate-specific g protein-coupled受体作为动脉粥样硬化的新型治疗靶点.pdf
- spider-venom peptides as bioinsecticides蜘蛛毒液肽作为bioinsecticides.pdf
- spider phobics more easily see a spider in morphed schematic pictures蜘蛛恐惧症者更容易看到一只蜘蛛在演变示意图的照片.pdf
- spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns光谱计数对脑脊液蛋白质动态范围的评估后损耗与plasma-designed immunoaffinity列.pdf
- spider-venom peptides as therapeutics蜘蛛毒液肽作为治疗.pdf
- spectroscopic investigations of the binding interaction of a new indanedione derivative with human and bovine serum albumins光谱调查绑定交互的新indanedione导数与人类和牛血清白蛋白.pdf
- spike timing and reliability in cortical pyramidal neurons effects of epsc kinetics, input synchronization and background noise on spike timing上升时间和可靠性在皮质锥体神经元epsc动力学的影响,输入在高峰时间同步和背景噪音.pdf
- spike timing dependent plasticity finds the start of repeating patterns in continuous spike trains高峰时间依赖性可塑性发现列车重复模式在连续上涨的开始.pdf
- spin state control of the perovskite rhco oxides自旋状态控制钙钛矿rhco氧化物.pdf
- structural versatility of bicellar systems and their possibilities as colloidal carriers结构bicellar系统的多功能性和胶体载体的可能性.pdf
- structural-functional characterization and physiological significance of ferredoxin-nadp+ reductase from xanthomonas axonopodis pv. citristructural-functional ferredoxin-nadp +还原酶的特性和生理意义、黄axonopodis pv。.pdf
- structure analyses of fe-based metallic glasses by electron diffraction由电子衍射结构分析fe-based金属玻璃.pdf
- structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs结构和催化性能的羧酸酯酶同功酶参与代谢激活高活性化合物.pdf
- structural simulation of a bone-prosthesis system of the knee joint结构模拟膝关节的bone-prosthesis系统.pdf
- structure and dynamics of the post-transcriptional mrna-processing machinery转录后的结构和动力学mrna-processing机械.pdf
- structural stability and vibrational analyses of haloselenonyl azides, xseo2-nnn, where x is f, cl, br结构稳定性和振动分析的haloselenonyl叠氮化,xseo2-nnn,其中x是f,cl,br.pdf
- structure and composition of leachfield bacterial communities role of soil texture, depth and septic tank effluent inputs的结构和组成leachfield细菌群落土壤质地的作用,深度和化粪池污水输入.pdf
- structure and function of snake venom proteins affecting platelet plug formation蛇毒蛋白的结构和功能影响血小板形成堵塞.pdf
- structure and reaction mechanism of basil eugenol synthase罗勒丁香酚合酶的结构和反应机理.pdf
文档评论（0）