synthesis of 1,2,3-triazole derivatives and in vitro antifungal evaluation on candida strains合成1 2 3-triazole衍生品和体外抗真菌评价念珠菌菌株.pdfVIP
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synthesis of 1,2,3-triazole derivatives and in vitro antifungal evaluation on candida strains合成1 2 3-triazole衍生品和体外抗真菌评价念珠菌菌株
Molecules 2012, 17, 5882-5892; doi:10.3390/molecule
OPEN ACCESS
molecules
ISSN 1420-3049
/journal/molecules
Article
Synthesis of 1,2,3-Triazole Derivatives and in Vitro Antifungal
Evaluation on Candida Strains
1 2 2
Reginaldo G. Lima-Neto , Nery N. M. Cavalcante , Rajendra M. Srivastava ,
3 4 1
Francisco J. B. Mendonça Junior , Almir G. Wanderley , Rejane P. Neves and
Janaína V. dos Anjos 2,*
1 Laboratório de Micologia Médica, Centro de Ciências Biológicas,
Universidade Federal de Pernambuco (UFPE), 50670-901, Recife, PE, Brazil
2 Laboratório de Síntese Orgânica, Departamento de Química Fundamental,
Universidade Federal de Pernambuco (UFPE), 50740-560, Recife, PE, Brazil
3 Laboratório de Síntese e Vetorização de Substâncias Bioativas,
Universidade Estadual da Paraíba (UEPB), 58058-420, João Pessoa, PB, Brazil
4 Laboratório de Farmacologia Pré-Clínica e Toxicologia de Produtos Bioativos,
Departamento de Fisiologia e Farmacologia, Universidade Federal de Pernambuco (UFPE),
50670-901, Recife, PE, Brazil
* Author to whom correspondence should be addressed; E-Mail: janaina.anjos@ufpe.br;
Tel.: +55-81-2126-7411; Fax: +55-81-2126-8440.
Received: 12 April 2012; in revised form: 3 May 2012 / Accepted: 5 May 2012 /
Published: 16 May 2012
Abstract: 1,2,3-Triazoles have been extensively studied as compounds possessing
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