原创力文档systematic review of dexketoprofen in acute and chronic pain系统回顾dexketoprofen的急性和慢性疼痛.pdfVIP
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systematic review of dexketoprofen in acute and chronic pain系统回顾dexketoprofen的急性和慢性疼痛
BMC Clinical Pharmacology BioMed Central
Research article Open Access
Systematic review of dexketoprofen in acute and chronic pain
† †
R Andrew Moore* and Jodie Barden
Address: Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford OX3
9DU, UK
Email: R Andrew Moore* - andrew.moore@pru.ox.ac.uk; Jodie Barden - jodie.barden@balliol.ox.ac.uk
* Corresponding author †Equal contributors
Published: 31 October 2008 Received: 25 March 2008
Accepted: 31 October 2008
BMC Clinical Pharmacology 2008, 8:11 doi:10.1186/1472-6904-8-11
This article is available from: /1472-6904/8/11
© 2008 Moore and Barden; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Dexketoprofen, an NSAID used in the management of acute and chronic pains, is
licensed in several countries but has not previously been the subjected of a systematic review. We
used published and unpublished information from randomised clinical trials (RCTs) of
dexketoprofen in painful conditions to assess evidence on efficacy and harm.
Methods: PubMed and Cochrane Central were searched for RCTs of dexketoprofen for pain of
an
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