the genus caesalpinia l. (caesalpiniaceae) phytochemical and pharmacological characteristics属石莲子l .(苏木科)的植物化学成分和药理特性.pdfVIP

Molecules 2012, 17, 7887-7902; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Review The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics 1 1 1 João L. Baldim Zanin , Bianca A. de Carvalho , Paloma Salles Martineli , Marcelo Henrique dos Santos 1, João Henrique G. Lago 2, Patrícia Sartorelli 2, Cláudio Viegas, Jr. 1,* and Marisi G. Soares 1,* 1 Institute of Chemistry, Federal University of Alfenas, 37130-000, Alfenas, MG, Brazil 2 Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, 09972, Diadema, SP, Brazil * Authors to whom correspondence should be addressed; E-Mails: cvjviegas@ (C.V.); marisigs@ (M.G.S.); Tel.: +55-35-3299-1466. Received: 20 April 2012; in revised form: 14 June 2012 / Accepted: 14 June 2012 / Published: 29 June 2012 Abstract: The genus Caesalpinia (Caesalpiniaceae) has more than 500 species, many of which have not yet been investigated for potential pharmacological activity. Several classes of chemical compounds, such as flavonoids, diterpenes, and steroids, have been isolated from various species of the genus Caesalpinia. It has been reported in the literature that these species exhibit a wide range of pharmacological properties, including antiulcer, anticancer, antidiabetic, anti-inflammatory, antimicrobial, and antirheumatic activities that have