the histopathology of septic acute kidney injury a systematic review感染性急性肾损伤的组织病理学系统回顾.pdfVIP

Available online /content/12/2/R38 Vol 12 No 2 Open Access Research The histopathology of septic acute kidney injury: a systematic review 1,2 1,3 1 1,4 Christoph Langenberg , Sean M Bagshaw , Clive N May and Rinaldo Bellomo 1Department of Intensive Care, Austin Hospital, Studley Rd, Heidelberg, Melbourne, Victoria 3084, Australia 2Howard Florey Institute, University of Melbourne, Grattan St, Parkville, Melbourne, Victoria, Australia 3Division of Critical Care Medicine, University of Alberta Hospital, University of Alberta, 112 Street NW, Edmonton, Alberta, BBT6G2B7, Canada 4Department of Medicine, Melbourne University, Grattan St. Parkville, Victoria 3052, Melbourne, Australia Corresponding author: Rinaldo Bellomo, rinaldo.bellomo@.au Received: 22 Nov 2007 Revisions requested: 24 Jan 2008 Revisions received: 26 Feb 2008 Accepted: 6 Mar 2008 Published: 6 Mar 2008 Critical Care 2008, 12:R38 (doi:10.1186/cc6823) This article is online at: /content/12/2/R38 © 2008 Langenberg et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Sepsis is the most common trigger of acute kidney (ATN). We found four primate studies. In these, seven out of 19 injury (AKI) in critically ill patients; understanding the structural (37%) cases showed features of ATN. We also found 13 rodent changes associated with its occ