using knowledge fusion to analyze avian influenza h5n1 in east and southeast asia使用知识融合分析禽流感h5n1病毒在东亚和东南亚.pdfVIP

Using Knowledge Fusion to Analyze Avian Influenza H5N1 in East and Southeast Asia 1,2 3 4 5 6 4 1,7 Erjia Ge , Robert Haining , Chi Pang Li , Zuguo Yu , Miu Yee Waye , Ka Hou Chu , Yee Leung * 1 Department of Geography and Resource Management, The Chinese University of Hong Kong, Hong Kong, China, 2 School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China, 3 Department of Geography, University of Cambridge, Cambridge, United Kingdom, 4 School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China, 5 School of Mathematics and Computational Science, Xiangtan University, Hunan Province, China, 6 School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China, 7 Institute of Environment, Energy and Sustainability, The Chinese University of Hong Kong, Hong Kong, China Abstract Highly pathogenic avian influenza (HPAI) H5N1, a disease associated with high rates of mortality in infected human populations, poses a serious threat to public health in many parts of the world. This article reports findings from a study aimed at improving our understanding of the spatial pattern of the highly pathogenic avian influenza, H5N1, risk in East- Southeast Asia where the disease is both persistent and devastating. Though many disciplines have made important contributions to our understanding of H5N1, it remains a challenge to integrate knowledge from different disciplines. This study applies genetic analysis that identifies the evolution of the H5N1 virus in space and time, epidemi