constitutive versus responsive gene expression strategies for growth in changing environments本构和响应基因的表达策略在变化的环境中成长.pdfVIP

Constitutive versus Responsive Gene Expression Strategies for Growth in Changing Environments Nico Geisel* Departament de Fisica Fonamental, Facultat de Fisica, Universitat de Barcelona, Barcelona, Spain Abstract Microbes respond to changing environments by adjusting gene expression levels to the demand for the corresponding proteins. Adjusting protein levels is slow, consequently cells may reach the optimal protein level only by a time when the demand changed again. It is therefore not a priori clear whether expression ‘‘on demand’’ is always the optimal st