control of tissue growth and cell transformation by the salvadorwartshippo pathway控制salvadorwartshippo组织生长和细胞转化的途径.pdfVIP

Control of Tissue Growth and Cell Transformation by the Salvador/Warts/Hippo Pathway Xiaomeng Zhang1,2, Felix A. Grusche1,2, Kieran F. Harvey1,2* 1 Cell Growth and Proliferation Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia, 2 Sir Peter MacCallum Department of Oncology, and Department of Pathology, University of Melbourne, Parkville, Victoria, Australia Abstract The Salvador-Warts-Hippo (SWH) pathway is an important regulator of tissue growth that is frequently subverted in human cancer. The key oncoprotein of