原创力文档effect of graded nrf2 activation on phase-i and -ii drug metabolizing enzymes and transporters in mouse liver分级效果nrf2激活大酒店和u2014u2014药物代谢酶和转运蛋白在小鼠肝脏.pdfVIP
- 6
- 0
- 约7.34万字
- 约 10页
- 2017-09-12 发布于上海
- 举报
effect of graded nrf2 activation on phase-i and -ii drug metabolizing enzymes and transporters in mouse liver分级效果nrf2激活大酒店和u2014u2014药物代谢酶和转运蛋白在小鼠肝脏
Effect of Graded Nrf2 Activation on Phase-I and -II Drug
Metabolizing Enzymes and Transporters in Mouse Liver
Kai Connie Wu, Julia Yue Cui, Curtis D. Klaassen*
Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, United States of America
Abstract
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that induces a battery of cytoprotective genes in
response to oxidative/electrophilic stress. Kelch-like ECH associating protein 1 (Keap1) sequesters Nrf2 in the cytosol. The
purpose of
您可能关注的文档
- early trauma and increased risk for physical aggression during adulthood the moderating role of maoa genotype早期创伤和风险增加身体侵犯在成年maoa基因型的缓和作用.pdf
- early steps of hiv-1 fusion define the sensitivity to inhibitory peptides that block 6-helix bundle formation早期的hiv - 1融合步骤定义块的敏感性,抑制肽6-helix束的形成.pdf
- early vascular alterations in sle and ra patients—a step towards understanding the associated cardiovascular risk早期血管改变在系统性红斑狼疮和类风湿性关节炎病人一步理解相关的心血管风险.pdf
- early warning indicators for hiv drug resistance in cameroon during the year 2010早期预警指标在2010年艾滋病病毒耐药性在喀麦隆.pdf
- early versus delayed decompression for traumatic cervical spinal cord injury results of the surgical timing in acute spinal cord injury study (stascis)创伤性颈脊髓损伤的早期和延迟减压手术时机的结果在急性脊髓损伤研究(stascis).pdf
- early reduction of microglia activation by irradiation in a model of chronic glaucoma尽早减少辐照小胶质细胞激活的慢性青光眼模型.pdf
- earthworms use odor cues to locate and feed on microorganisms in soil蚯蚓使用气味信号来定位和饲料在土壤微生物.pdf
- earthworm effects without earthworms inoculation of raw organic matter with worm-worked substrates alters microbial community functioning蚯蚓的影响没有接种蚯蚓的原始有机质worm-worked基质改变微生物群落功能.pdf
- early-onset ventilator-associated pneumonia in adults randomized clinical trial comparison of 8 versus 15 days of antibiotic treatment成人与机械通气相关肺炎早发性的随机临床试验比较8和15天的抗生素治疗.pdf
- early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents pulmonary hypertension in monocrotaline-injured rats早期治疗与烟曲霉素、蛋氨酸aminopeptidase-2的抑制剂,防止在monocrotaline-injured大鼠肺动脉高压.pdf
- DB37_T_2810_2016_动物疫病流行病学监测技术.pdf
- 人教版八年级历史下册人民共和国成立教学设计(可编辑修改版)..pdf
- XX学校2026年春季学期学生上下学交通安全管理制度.docx
- (完整版)人教版九年级下册化学酸碱盐习题汇编2-推荐文档.pdf
- XX中学2026年4月“校园之星”评选活动方案及评分细则.docx
- 执业药师之中药学综合知识与技能考试易错知识点总结.pdf
- XX学校2026年春季学期教育督导评估档案材料整理规范.docx
- XX学校2026年春季学期教育集团化办学工作推进情况汇报.docx
- XX学校2026年春季学期学生宿舍夜间查寝管理规定.docx
- 当代中外名人掌纹分析(最新整理).pdf
文档评论（0）