不得不知的有机氧化剂(英文).docxVIP

?One 、MCPBA3-Chloroperoxybenzoic acid, MCPBA, meta-Chloroperbenzoic acidMCPBA is a strong oxidizing agent, which is comparable with other peracids. Advantages of 3-chloroperbenzoic acid is its handling, because it is present as powder, which can be kept in the refrigerator. Nevertheless, material of purity 75% is rarely available commercially, since the pure compound is not particularly stable. Therefore the transport in airplanes with a content of 72% is forbidden. Main pollution is 3-chlorobenzoic acid (10%) as well as for safety reasons water. MCPBA is versatile applicable as peracid for use in laboratories. Main areas are the oxidation ofaldehydes and ketones to esters (Bayer-Villiger-Oxidation) olefines to epoxides sulfides to sulfoxides and sulfonesamines to nitroalkanes, nitroxides or N-oxides However, for reasons of the atomic economy, the use of MCPBA in production should be avoided. The research concentrates within this area rather on the use of hydrogen peroxide in connection with suitable catalysts or in situ generated, simpler peracids, such as peracetic acid or on potassium peroxymonosulfate (Oxone). In many reactions MCPBA with an outstanding reactivity is however more selective than hydrogen peroxide and other peracids.Name ReactionsCope EliminationPrilezhaev ReactionRubottom OxidationRecent LiteratureUse of a solvent with greater density than the fluorous phase is an alternative to the U-tube method in phase-vanishing reactions in cases where both reactants are less dense than the fluorous phase.N. K. Jana, J. G. Verkade, Org. Lett.,2003, 5, 3787-3790.N. K. Jana, J. G. Verkade, Org. Lett.,2003, 5, 3787-3790.N. K. Jana, J. G. Verkade, Org. Lett.,2003, 5, 3787-3790.The results of a highly diastereoselectiveepoxidation of allylicdiols derived from Baylis-Hillman adducts are reported.R. S. Porto, M. L. A. A. Vasconcellos, E. Ventura, F. Coelho, Synthesis, 2005, 2297-2306.A clean and efficient and metal-free diacetoxylation reaction of alkenes using com