质和原核生物、真核生物蛋白质的亚细胞定位预测研究-附件2(Prediction of subcellular localization of proteins in prokaryotes and eukaryotes - Appendix 2).docVIP
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质和原核生物、真核生物蛋白质的亚细胞定位预测研究-附件2(Prediction of subcellular localization of proteins in prokaryotes and eukaryotes - Appendix 2)
质和原核生物、真核生物蛋白质的亚细胞定位预测研究-附件2(Prediction of subcellular localization of proteins in prokaryotes and eukaryotes - Appendix 2)
Annex 2
Format of Chinese and English Abstracts
Authors name: Chen Yingli
Title: subcellular localization prediction of apoptosis proteins and prokaryotes and eukaryotic proteins
Biography: Chen Yingli, female, born in August 1974, studied in September 2002 with Prof. Li Qianzhong from Inner Mongolia University and received his doctorate in July 2007.
Chinese abstract
With the successful implementation of the human genome project, more and more protein sequences have been determined, but the understanding of protein structure and function is far behind the sequence determination. Because the subcellular location of proteins is closely related to their function in cells, the study of subcellular localization of proteins is an important tool for the study of protein function. By means of experiments means to determine the subcellular location of a protein is time-consuming and high cost, and the experiment may encounter lots of difficulties, thus the theoretical or computational methods for protein subcellular localization information becomes more and more important, this work has become a research hotspot.
This paper from two aspects: functional classification and classification of organisms, study the subcellular location of apoptosis protein and prokaryotic and eukaryotic proteins prediction problems in prokaryotes focus on Gram negative bacteria protein as the research object. The main results of this paper are as follows:
1. of the least increment prediction algorithm (ID) based on the proposed two new combination forecasting discrete incremental algorithm fusion algorithm (IDF) and combined with the discrete incremental algorithm of support vector machine (ID_SVM), and for the first time applied to the prediction of protein subcellular localization of apoptosis, while in the two cell apoptosis protein test the data sets and the results of t
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