11-慢性心衰中的中枢性睡眠呼吸暂停（11- central sleep apnea in chronic heart failure）.doc

11-慢性心衰中的中枢性睡眠呼吸暂停（11- central sleep apnea in chronic heart failure） Central sleep apnea in chronic heart failure Li Wei, , Li Mingjia , Huang Xiantao (904-5133), Wang Kang (904-5135), Zhang heavy Disease physiology experiment 04 groups, 04 basic classes [Keywords] CHF, CSA, BNP Chronic heart failure (Chronic, heart, failure, CHF) is a heart failure caused by cardiovascular or other multisystem disorders. Heart failure is still a cardiovascular disease with a high morbidity and mortality, and is the leading cause of hospitalization in people over the age of 65. Central sleep apnea (Central sleep, apnea, CSA) is sleep disordered breathing (Sleep disordered, breathing, SDB) a loss generated during the suction process due to the failure of the short central respiratory rhythm, obstructive sleep disorder and expiratory pause (OSA) on the contrary. CSA and OSA are common in patients with severe chronic heart failure, and studies have shown that CSA is associated with a significant prognosis for heart failure, whereas OSA is not. CSA and CHF are reciprocal causation, a vicious cycle, which seriously affects the prognosis of patients. This review summarizes the mechanisms of action of CSA and CHF, the clinical symptomatic treatment of CSA, and the new guiding role of BNP in the diagnosis of CHF associated with CSA. Mechanisms of action of 1.CSA and CHF: It includes two aspects: CHF produces and aggravates CSA; CSA aggravates CHF and affects prognosis. Pathogenesis of 1.1.CSA: The control of respiratory rhythm in 1.1.1. normal body includes two points: the control of the autonomic nervous metabolism system, the control of respiratory rhythm, and the control of the respiratory rhythm by the waking state. The autonomic nervous metabolic system controls respiratory rhythms, i.e., chemical signals such as changes in CO2 and H+ concentrations that regulate respiration, which is the most sensitive and rapid regulation of respiratory movements. The c