水浴式灭菌柜的工作原理及其验证（Working principle and verification of water bath sterilizer）.docVIP

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水浴式灭菌柜的工作原理及其验证（Working principle and verification of water bath sterilizer）.doc

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水浴式灭菌柜的工作原理及其验证（Working principle and verification of water bath sterilizer）

水浴式灭菌柜的工作原理及其验证（Working principle and verification of water bath sterilizer） Working principle and verification of water bath sterilizer Abstract: the structure and working principle of water bath sterilizer are expounded. The control points of sterilizer are emphasized, and the content, operation process and data analysis of sterilizer are simply analyzed. Key words: water bath sterilizer; working principle; verification; sterilization; data analysis In many of the production of drugs, in order to ensure the quality of medicines are generally required for sterilization, such as infusion, water injection, oral liquid, even in the solid preparation of raw materials in the Chinese herbal medicines are needed to ensure the quality of medicines through sterilization, sterilization visible is a very important link in the production of drugs. The sterilization method can be divided into physical sterilization and chemical sterilization, aseptic manipulation, as shown in table 1. Table 1 Classification of sterilization methods physical sterilization Chemical sterilization Aseptic manipulation Heat, filtration, radiation, ultraviolet, microwave Chemical agents, gases According to the different object of sterilization, proper sterilization methods should be selected, and physical sterilization is generally adopted in the pharmaceutical industry, among which the most commonly used sterilization methods are dry heating sterilization and hot and humid sterilization. The focus is used for water bath sterilizer sterilization liquid preparation (hereinafter referred to as the sterilization cabinet), it is a kind of typical pharmaceutical sterilization equipment used in sterilization, is widely used in the liquid medicine production enterprises, the working principle and verification are briefly discussed. 1. The structure and working principle of the sterilizer 1.1 sterilizing cabinet structure The main structure of sterilizing cabinet is a cavity (cabinet compression), water dist