并会减少粒线体摄入Rh123的量.PPT

Pharmacological study of Phellinus linteus Phellinus linteus (PL), a traditional medicinal mushroom, for the treatment of various diseases. Recent studies have shown that PL has Hispolon, an active polyphenol compound, is known to possess potent induces apoptosis in cancer cells. Hispolon induces apoptosis in cancer cells : the efficacy of hispolon in human gastric cancer cells and explored the cell death mechanism. Hispolon induced ROS-mediated apoptosis in gastric cancer cells. antiviral antiproliferative immunomodulatory activity antioxidant activity antiviral of Hispolon : hispolon showed considerable antiviral activity against influenza viruses type A and B. antiproliferative of Hispolon : Hispolon also suppress mitogen induced proliferation of spleen lymphocytes of mice. Isolation and purification of hispolon 最近研究表示, PL 有抗發炎, antimutagenicity, 和抗菌作用; 刺激免疫; 並且禁止腫瘤成長和轉移 Hispolon 禁止人的單核細胞化合光反應和並且壓制mitogeninduced 老鼠脾臟淋巴細胞的擴散 Hispolon, 1996 年一種黃色顏料第一次被發現了在Inonotus hispidus The apoptosis effect of hispolon from Phellinus linteus (Berkeley Curtis)Teng on human epidermoid KB cells Journal of Ethnopharmacology 105 (2006) 280–285 Introduction 桑黃（Phellinus linteus）為一種寄生於闊葉樹上的刺革菌科菇類，因其生長緩慢，取得不易，加上難以人工栽培，故有「夢幻菇蕈」之稱。 Phellinus linteus(PL)的成分介紹 Polysaccharides Triterpenoids phenolics Meshimakobnol Proteins Mineral gastroenteric disorder peptic ulcers lymphatic disease various cancers anti-inflammatory antimutagenicity antibacterial effects stimulates immunity inhibits tumor growth and metastasis Hispolon 分子結構: 化學名: 6-(3,4-dihydroxy-phenyl)-4-hydroxy-hexa- 3,5-dien-2-one 分子式: C12H12O4 分子量: 220.22 Hispolon,a yellow pigment was first found in Inonotus hispidus in 1996 That hispolon could induce human epidermoid KB cell apoptosis accompanied by the collapse of mitochondrial membrane potential. treatment of oral cancer Free Radical Biology Medicine 45 (2008) 60–72 treatment of gastric cancer Other studie