中药煎剂内服外洗治疗复发性尖锐湿疣临床探究.docVIP

中药煎剂内服外洗治疗复发性尖锐湿疣临床探究 　【摘要】 　　【目的】观察中药煎剂内服外洗对复发性尖锐湿疣临床复发的影响。【方法】采用半随机单盲法将１２８例患者分为２组，治疗组６５例在微波除疣治疗的基础上，同时给予口服薏苡仁甘草汤煎剂加自拟消疣汤煎剂外洗患处皮损，每天１次；对照组６３例给予单纯微波除疣治疗。两组均以１个月为１个疗程。观察两组治疗３个疗程内及随访６个月内临床复发情况。【结果】治疗１、２、３个月内治疗组临床复发例数分别为３７例（５６９２％）、２５例（３８４６％）、１１例（１６９２％），对照组分别为５２例（８２５４％）、４７例（７４６０％）、３６例（５７１４％），治疗组复发率明显低于对照组（Ｐ＜００５）。随访２、４、６个月内治疗组临床复发例数分别为１２例（１８４６％）、１４例（２１５４％）、１５例（２３０８％），对照组分别为４１例（６５０８％）、４５例（７１４３％）、４６例（７３０２％），治疗组复发率明显低于对照组（Ｐ＜００５）。【结论】中药煎剂内服外洗治疗复发性尖锐湿疣具有较好的近期和远期疗效。 【关键词】 尖锐湿疣／中药疗法；薏苡仁甘草汤／治疗应用；消疣汤／治疗应用；外治法 　　Abstract： Objective To observe the therapeutic effect of oral use and external application of Chinese herbal decoction for the treatment of recurrent condyloma acuminatum (RCA).MethodsOne hundred and twentyeight RCA patients were divided into two groups by half randomization and single blind method.The treatment group (N=65) received oral use of Yiyiren Gancao Decoction and washing the lesion with selfmade Xiaoyou Decoction once a day except the microwave radiation therapy.The control group (N=63) received microwave radiation therapy alone.One month constituted one treatment course.The recurrence of RCA in the two groups was investigated within 3 treatment courses and within 6 months of followup.Results In the treatment groups,there were 37 (5692%) recurrent patients during the 1st treatment course,25 (3846%) during the 2nd course,and 11 (1692%) during the 3rd course;in the control group,there were 52 (8254%) recurrent patients during the 1st treatment course,47 (7460%) during the 2nd course,and 36 (5714%) during the 3rd course.The recurrence rate in the treatment group was lower than that in the control group (P＜005).In the treatment group,there were 12 (1846%) recurrent patients within 2 months of followup,14 (2154%) within 4 months of followup,and 15 (2308%) within 6 months of followup;in the control group,there were 41 (6508%) recurrent patients within 2 months of followup,45 (7143%) within 4 months of followup,and 46 (7302%) within