中药雾化透皮法治疗痹病临床探究.docVIP

中药雾化透皮法治疗痹病临床探究 　【摘要】 目的 研究中药汽疗仪辨证用药雾化透皮外治寒湿阻络证、寒热错杂证、痰瘀阻络证为主的风湿、类风湿、强直性脊柱炎、颈肩腰腿痛的临床疗效及安全性。方法 将376例风湿、类风湿、强直性脊柱炎、颈肩腰腿痛患者随机按3∶1比例设立对照；治疗276例依据临床证型分别选用痹复康Ⅰ、Ⅱ、Ⅲ号浴剂；对照组100例用食醋、羌活、威灵仙，疗程均为20天，对临床疗效、观察指标、实验室指标进行综合评估。结果 治疗组对风湿、类风湿、强直性脊柱炎、颈肩腰腿痛、寒湿阻络证、寒热错杂证、痰瘀阻络证总有效率分别为98.89%，94.00%，96.15%，94.05%，98.22%，94.84%，95.52%；对照组分别为46.67%，20.00%，13.33%，45.00%，41.46%，10.53%，47.62%，显示中药汽疗仪辨证施药雾化透皮法对四病三证的总有效率均超过90%，对照组总有效率均未能达到50%，两组病证分别相比较，差异有统计学意义（P＜0.01或P＜0.001）；治疗组在改善临床症状、体征和实验室指标等方面的疗效肯定（P＜0.05或P＜0.01），研究过程中未发现严重的不良反应。结论 中药汽疗仪辨病辩证用药雾化透皮法是治疗以寒湿阻络证、寒热错杂证、痰瘀阻络证为主的风湿、类风湿、强直性脊柱炎、颈肩腰腿痛等病证有肯定疗效的一种新方法且较安全。 【关键词】 痹证/中药疗法；皮肤吸收；中药离子透入 ［Abstract］ Objective To research the therapeutic effect and safety of nebulizer transdermal drug by vapour therapy in dialectical treating on beriberoid disease，rheumatoid，ankylosing spondylitic，pains on neck-shoulder-waist-leg，which were caused by retention of cold-damp in the collaterals，cold-heat complicated syndrome，obstruction of collaterals cold hygrosis.Methods Three hundred and seventy-six cases were randomly divided into two groups.Two hundred and seventy-six cases were treated with Bifukang Balneum Ⅰ，Ⅱ，Ⅲ as the study group，while 100 cases were treated with vinegar and Chinese clematis root as the control group，with a treatment course of 20 days for both groups.Therapeutic effect，observation index and laboratory index were compositively evaluated.Results The total effective rates for beriberoid disease，rheumatoid，ankylosing spondylitic dialectical，pains on neck-shoulder-waist-leg，retention of cold-damp in the collaterals，cold-heat complicated syndrome，obstruction of collaterals cold hygrosis in the study group were 98.89%，94.00%，96.15%，94.05%，98.22%，94.84%，95.52%，while the control group were 46.67%，20.00%，13.33%，45.00%，41.46%，10.53%，47.62%.The total effective rate of the study group was more than 90% while that of the control group was less than 50%.There was great difference in two groups（P＜0.01 or P＜0.001）.The therapeutic effect of the study group o