水凝胶(清得佳)治疗糖尿病足临床疗效分析.docVIP

水凝胶(清得佳)治疗糖尿病足临床疗效分析 　【关键词】 水凝胶(清得佳)；,,糖尿病足；,,复合碘 　　摘要：目的：观察、分析水凝胶(清得佳)对糖尿病足(Diabetes Foot DF) 的治疗效果。方法：同期观察60例DF患者，分成两组，在基础治疗相同的情况下，治疗组（30例）采用在创面上均匀涂上一层约1～2cm厚度的水凝胶(清得佳)外用包扎治疗。对照组（30例）采用复合碘外用治疗。观察水凝胶(清得佳)对DF 创面的动态变化（脱腐、肉芽生长、表皮生长的情况）。结果：治疗组总有效率为100%，对照组为82%，治疗组疗效优于对照组（Plt;0.01）。水凝胶外敷创面是一种湿润疗法,对创面无刺激，可为创面提供一个良好的、适合生长的湿润生态环境，并在改善DF创面的基底条件、促进肉芽及表皮生长方面，疗效优于复合碘（Plt;0.05）。结论：水凝胶(清得佳)治疗DF有较好疗效。 　　关键词： 水凝胶(清得佳)； 糖尿病足； 复合碘 　　Analysis of Clinical Therapeutic Effect in Diabetes Foot Patients with Hydrogel 　　Abstract： Objective： To investigate and analysis the therapeutic efficacy of hydrogel in Diabetes Foot (DF).Method: Sixty DF patients were randomly divided into two groups;based on the same basic treatment,1)Hydrogel group(n=30):the raw surface was overlayed with 1～2cm thickness hydrogel,then bandaged.2)control group(n=30):the raw surface was treated with the compound iodine.To explore the dynamic changes( the condition of aporotten,granulation growth and epidermis growth) of raw surface after using the hydrogel.Result:Hydrogel group?s total effective power has reached 100%,which was obviously better than in control group(only 82%,Plt;0.01) The raw surface overlayed with hydrogel was a moist therapy with no stimulus-reaction,which could provide a favourable and suitable ecological environment for growth;which could also improve the basal body condition of the raw surface and enhance the growth of granulation and epidemis,its therapeutic effect was better than compound iodine(Plt;0.05).Conclusion:Hydrogel has a very good therapeutic effect in DF patients. 　　Key words： Hydrogel； DF； Compound iodine 糖尿病病人因神经病变，使足部失去感觉，并出现畸形和周围血管病变，使足部缺血，局部组织失去活力，且合并感染的足称之为糖尿病足（Diabetes Foot DF）。DF是一种严重的糖尿病慢性并发症，是非外伤性截肢的首要原因。当前国内外文献资料报道对DF的治疗方法较多，其治疗原则主要是内外结合，保存肢体：内以全身基础综合治疗（控制血糖、抗炎、改善外周血液循环、营养支持等）为主［1，2］。外以创面治疗、促进愈合为主。在局部创面治疗方面，现有资料报道较多采用的方法有：表皮生长因子外敷、中西医药物结合外用、复合碘外敷等［3］。而水凝胶(清得佳)在DF创面上的应用则鲜有报道。本文取于我院自2002年至2005年收治的DF患者60例，30例为治疗组，创面应用水凝胶(清得佳)，30例为对照组，创面应用复合碘。治疗组在脱腐、肉芽生长、表皮生长方面均优于对照组。本文通过对该60