淮安市成人结核杆菌感染情况抽样调查探究.docVIP

淮安市成人结核杆菌感染情况抽样调查探究 　论文作者：刘林飞 左于会 李卓 叶隆昌 曹建国 陈万林 关键词：淮安 【摘要】 目的 了解我市成人结核杆菌感染情况，分析原因，探讨如何更好地降低结核杆菌感染率。方法 在所辖洪泽县和涟水县各抽取1个乡镇，以20～55岁健康村民为研究对象，用5TU剂量的结核菌素纯蛋白衍化物（TB-PPD）常规皮试，72h后查验反应，对结果进行统计分析。结果 查验对象共23503例，其中反应阴性率25.83%，阳性率63.29%,强阳性率10.88%；单因素及多因素统计分析结果均证实：地区(县)、性别、年龄3个变量均有显著的统计学意义。结论 本组受试对象的结核杆菌平均感染率74.17%；男性比女性更容易受到结核杆菌感染；经济是与感染有关的一个因素；“项目县”的实施，特别是线索调查对降低结核杆菌感染率是有明显效果的。 【关键词】 结核杆菌； 结核菌素纯蛋白衍化物； 皮试 The study on sampling survey of tubercle bacillus infection status in adults of Huaian LIU Lin-fei, ZUO Yu-hui, LI Zhuo, et al. Center for Disease Control and Prevention of Huai’an City, Jiangsu 223001,China 【Abstract】 Objective In order to realize tubercle bacillus infection status in adults of Huaian， to find out its reason, and to probe into the way of decreasing the infection rate of tubercle bacillus.Methods The healthy peasants within 20-55 years old at 2 towns in 2 counties were tested with purified protein derivative of tubercle bacillus(TB-PPD), the outcome was observed over 72 hours after testing. Results A total of 23503 subjects tested were observed, the negative rate is 25.83%, the positive rate is 63.29%, the strong positive rate is 10.88%. Both univariate and multivariate analyses confirm that all three variables(county,sex,age) have highly significant differences statistically. Conclusion The average infection rate of the subjects is 74.17%. Men are more prone to tubercle bacillus infection than women. Income is one of factors associated with the infection. The implementation of tuberculosis control program，especially the clue investigation of tuberculosis patients have had an obvious effect in decreasing the infection rate of tubercle bacillus. 【Key words】 tubercle bacillus; TB-PPD; dermatic test 根据《成人接种卡介苗(BCG)预防结核、肿瘤等病监测研究》课题方案，我们于1997～1998年对我市23503例研究对象进行了结核菌素纯蛋白衍化物（TB-PPD）常规皮试，以便从中剔除活动性结核病患者后对课题的实施。现对PPD皮试结果进行统计和研究，分析结核杆菌感染的流行因素，旨在对如何降低结核杆菌感染率方面提供有益的参考。 1 材料与方法 1.1 研究对象 在所辖13个县区中按6：1的比例随机各抽取1个县（区），在被抽的两个县（区）中再各抽取一个乡镇（涟水县唐集镇、洪泽县岔河镇），以镇内的所有20～5