无症状高尿酸血症合并心血管疾病诊治建议专家共识(终稿)(Expert consensus on the diagnosis and treatment of asymptomatic hyperuricemia complicated with cardiovascular disease (final version)).docVIP

无症状高尿酸血症合并心血管疾病诊治建议专家共识(终稿)(Expert consensus on the diagnosis and treatment of asymptomatic hyperuricemia complicated with cardiovascular disease (final version)).doc

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无症状高尿酸血症合并心血管疾病诊治建议专家共识(终稿)(Expert consensus on the diagnosis and treatment of asymptomatic hyperuricemia complicated with cardiovascular disease (final version))

无症状高尿酸血症合并心血管疾病诊治建议专家共识(终稿)(Expert consensus on the diagnosis and treatment of asymptomatic hyperuricemia complicated with cardiovascular disease (final version)) Expert consensus on the diagnosis and treatment of asymptomatic hyperuricemia complicated with cardiovascular disease (final version) Elevated serum uric acid levels are associated with abnormal nucleic acid metabolism and decreased renal excretion in the body. In normal circumstances, uric acid saturation in the blood is 6.7mg/dl, and hyperuricemia is common in the world (Hyperuricemia, The diagnostic criteria for HUA are defined as serum uric acid levels, male 420umol/l (7mg/dl), female 357umol/l (6mg/dl), and HUA without episodes of gout is referred to as asymptomatic HUA. HUA is often associated with traditional metabolic cardiovascular risk factors such as hypertension, hyperlipidemia, type 2 diabetes mellitus, obesity, and insulin resistance. For a long time, HUA has been regarded as a marker of metabolic abnormalities. Over the past 20 years the more than 10 large-scale prospective clinical research, about 100 thousand cases of the above observation object, using multivariate regression analysis confirmed that HUA is an independent risk factor for cardiovascular disease, there is no evidence that lowering uric acid can reduce the risk of cardiovascular events, so that the South did not put HUA out independent risk factors for cardiovascular disease the. In view of the fact that hyperuricemia is closely related to the adverse prognosis of the blood vessel, heart and kidney, urate lowering therapy is expected to be a new approach for the prevention and treatment of cardiovascular diseases. In 2002, the Japanese Association for the nucleic acid metabolism of gout was the first in the world to suggest that asymptomatic HUA should be stratified according to cardiovascular risk factors or coexisting cardiovascular diseases. In our country there are a large number of asymptomatic HUA patients with multiple

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