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直肠分期(Rectal staging)
直肠分期(Rectal staging)
The overall 5 year survival rate of rectal cancer is about 65.2%, and the 5 year survival rate is as follows:
The 0 stage was confined to mucosa without lymph node metastasis: 93.2%
Stage I was confined to the muscularis propria without lymph node metastasis: 91.4%
Stage II tumor invasion exceeded the muscularis propria, but there was no lymph node metastasis: 76.4%
Metastasis of stage III lymph node: 58%
Distant metastasis (liver, lung, etc) or peritoneal metastasis in stage IV: 14.6%
The prognosis of rectal cancer is better. If the early operation can be found in time, most patients can be cured. The majority of rectal cancer in our country have been found late, and the total resection rate is about 60% at present, and more in the middle and late stages.
The patient is T3N2M0, belonging to the IIIC phase. Such patients must be surgically removed and then treated with chemotherapy and radiation. Recommended program:
1.FOLFOX4 (chemotherapy regimen abbreviation)
Asha Leigh Per (Oxaliplatin) 85 mg/m2, intravenous drip for first days;
Leucovorin (Leucovorin, CF) 200 mg/m2/ days, 2 hours before fluorouracil (5-FU), first to 2 days;
Fluorouracil (5-FU) was given intravenously for 400 mg/m2/ days and then continued for 600 mg/m2/ days, 22 hours, for first to 2 days;
14 days later, repeated treatment, a total of 12 courses. 2.FOLFOX6 (chemotherapy regimen abbreviation)
Asha Leigh Per (Oxaliplatin) 100 mg/m2, intravenous drip for first days;
Leucovorin (Leucovorin, CF) 200 mg/m2/ days, 2 hours before fluorouracil (5-FU), first to 2 days;
Fluorouracil (5-FU) 400 mg/m2, intravenous injection, first days, then 2400 mg/m2, 46 hours, continuous intravenous drip, first to 2 days. 3.28 days later, repeated treatment, a total of 6 courses. Capecitabine (Xeloda 1000 Capecitabine, Xeloda) mg/m2, oral, 2 times in 1 days, 2 weeks, 1 weeks (1 sessions), a total of 8 courses. Stage III: the average survival rate at 5 years is 56%, and many patients will be cured.
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