细胞凋亡研究进展（Research progress of apoptosis）.docVIP

细胞凋亡研究进展（Research progress of apoptosis） Research progress of apoptosis Abstract: Cell apoptosis, oncosis and necrotic cell death is irreversible cell injury functional definition, apoptosis is one of the cell death, the total end changes and necrosis occurred in the living on behalf of local tissue after cell death, is a kind of morphological diagnosis. In addition to cell apoptosis, there is another form of cell death or necrosis like death, said: the oncosis oncosis (oncosis), namely death (swelling death), was characterized by cell damage process of cytoplasmic swelling and karyolysis. Although there are still many problems and even the key questions are not clear, but the research in recent years the biochemical reaction mechanism in apoptosis signal transduction, cell apoptosis and apoptosis gene regulation and other aspects have made significant progress. Keywords: apoptosis, mitochondrial cysteine protease It is generally accepted that apoptosis plays an important role in cancer and other diseases. It has been widely studied in many biological fields. Since 1972, Kerr proposed the concept of cell apoptosis, from late 80s began to become a research hotspot in tumor etiology, pathology, understanding of apoptosis gradually, the molecular mechanism of apoptosis occurred more and more thorough understanding, but also found that this process is not as simple as originally thought, but contains a complicated regulatory mechanism the. The stability of organism environment depends not only on the proliferation and differentiation of cells, but also on the apoptosis of cells. Apoptosis (apoptosis), also known as programmed cell death, is one of the most important biological phenomena in biology. From nematodes to higher mammals, from embryos to adults, from physiology to pathology, from birth to death, different cells in the body have more of this form of death. More than 100 years ago, Carl Vogt had found this form of death. In 1972, Kerr et al. Re proposed the stud