药物分析技术应用研究新进展 - 药学进展.PDFVIP

PROGRESS IN PHARMACEUTICAL SCIENCES 2014,38 4 :241-251 ( ) 241 ·前沿与进展· A D VA N C E S I N P H A R M A C E U T I C A L S C I E N C E S 药物分析技术应用研究新进展 杨漾，严方，陈金龙，叶慧，郑枫，李博，狄斌 * （中国药科大学药物分析教研室，江苏 南京 210009） [ 摘要 ] 通过对 2012 年我国学者在国内外发表的有关药物分析技术应用研究论文进行检索和整理，分类综述针对化学药物、基因工程药物 以及中药等各类药物或生物样本的过程分析技术、高通量筛选分析技术、固态性质表征分析技术、杂质谱检测分析技术、体内样本分析技术、 中药分析技术、生化药物分析技术等的应用研究新进展。 [ 关键词 ] 药物分析技术；生产过程分析；高通量筛选；固态性质表征；杂质谱检测；体内样本分析；中药分析；生化药物分析 [ 中图分类号 ] R917 [ 中图分类号 ] A [ 文章编号 ]1001-5094(2014)04-0241-11 Recent Progress in Applications of Pharmaceutical Analytical Techniques YANG Yang, YAN Fang, CHEN Jinlong, YE Hui, ZHENG Feng, LI Bo, DI Bin ( Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China ) [Abstract] Through retrieving,analyzing and summerizing the research papers relevant to the applications of pharmaceutical analytical techniques published at home and abroad by Chinese scholars in 2012, the recent progress in the applications of various pharmaceutical analytical techniques for chemicals, genetically engineered drugs and traditional Chinese medicines,including process analytical techniques, high throughput screening techniques, solid-state characterization techniques, impurity profile detection techniques, in vivo sampling analytical techniques, traditional Chinese medicines analytical techniques, biochemical drug analytical techniques, etc, was reviewed. [Key words] pharmaceutical analytical technique; production process analysis; high throughput screening; solid-state characterizatio