影响肺癌术后复发转移的因素（Factors affecting recurrence and metastasis of lung cancer after operation）.docVIP

影响肺癌术后复发转移的因素（Factors affecting recurrence and metastasis of lung cancer after operation） Factors affecting recurrence and metastasis of lung cancer after operation Recurrence and metastasis of lung cancer is one of the important factors that affect the survival of lung cancer patients. According to statistics, even in patients with stage I non-small cell lung cancer, radical resection has been performed, and there are still more than 30% of the patients who cannot be cured or died. This is largely due to postoperative recurrence and metastasis. Therefore, understanding the pathological mechanism of recurrence and metastasis of lung cancer is of great significance for the prevention of recurrence and metastasis. Here are some of the major factors that affect the recurrence and metastasis of non-small cell lung cancer after surgery. Causes of recurrence and metastasis after 1.NSCLC It has been confirmed that cancer cells from the initial mutation to form a mass of less than 3mm, the capillary formation and grow into them, because the capillary basement membrane is not continuous, cancer cells can easily enter the blood circulation to systemic spread of opportunity. That is, in the development of malignant tumors, tumor cells can spread early and survive in the blood circulation, lymph tract, bone marrow and various tissues and organs, forming a micro metastasis. The micro metastases did not form nodules in the body, nor any clinical manifestations, routine methods such as science, such as clinical pathological methods are difficult to detect, at this time, although through the improvement of operation more radical resection of the primary tumor and lymph node dissection, but invisible micrometastases actually already exists. The presence of micrometastasis is the source of recurrence after NSCLC and the basis of metastasis. Surgical treatment is also one of the reasons for the recurrence and metastasis of NSCLC after operation. On the one hand, the operation may caus