含氟窝沟封闭剂与玻璃离子封闭剂抑制-第三军医大学学报.DOCVIP

含氟树脂封闭剂与玻璃离子封闭剂抑制牙釉质脱矿的体外研究 刘 桥，林居红，王金华 （重庆医科大学附属口腔医院 预防科，重庆 400015） 摘 要： 目的 观察和比较含氟树脂封闭剂与玻璃离子封闭剂在体外抑制牙釉质脱矿的能力。方法 将30个无龋新鲜拔出的人类第三磨牙随机分为3组，每组10个标本，在颊面釉质制备洞型，分别用含氟树脂封闭剂(ClinproTMsealant)，玻璃离子封闭剂(Fuji Ⅸ GP)和不含氟树脂封闭剂(Concise)进行充填，经300次热循环处理后测定每组标本封闭剂边缘外1mm宽釉质的表面显微硬度值，然后将标本放入人工脱矿液中7d，最后再次测定脱矿后每组标本釉质的表面显微硬度值。结果 脱矿实验后每组标本表面显微硬度（维氏硬度值，单位HV）平均下降值分别为：ClinproTMsealant组（87.30±23.84）HV，Fuji Ⅸ GP组（76.90±27.75）HV，Concise组（147.67±46.42）HV。ClinproTMsealant组和Fuji Ⅸ GP组均与Concise组有显著性差异（P0.01），而ClinproTMsealant组和Fuji Ⅸ GP组之间差别无统计学意义（P0.05）。结论 含氟树脂封闭剂与玻璃离子封闭剂都能够有效减少封闭剂边缘釉质的脱矿量，封闭剂所释放的氟离子在某种程度上为邻近釉质抵抗体外脱矿提供保护。 关键词：含氟封闭剂；玻璃离子；脱矿；龋病 中图法分类号： R781.05 文献标识码: A 基金项目：重庆医科大学校级科研课题（编号XBYB2007065） Supported by the Scientific Research Funds of Chongqing Medical University (XBYB2007065) 作者简介：刘 桥，女，重庆人，硕士研究生，主要从事儿童牙病防治方面的研究。 电话E-mail: anita3281983@ 通信作者：林居红，电话：（0238401E-mail:juhonglin@ 收稿日期：2008-07-02 ；修回日期： An in vitro study on inhibition of enamel demineralization by fluoride-releasing resin sealant and glass ionomer sealant LIU Qiao, LIN Ju-hong, WANG Jin-hua (Department of Preventive Dentistry, The Affiliated Hospital of Stomatology, Chongqing Medical University, Chongqing 400015, China) Abstract: Objective To compare the inhibitory effect of fluoride-releasing resin sealant and glass ionomer sealant on enamel demineralization in vitro. Methods Thirty noncarious human third molars extracted were randomly divided into three groups with 10 in each.Cavity was placed on buccal surfaces of the molars, then filled with fluoride-releasing resin sealant (ClinproTMsealant), glass ionomer sealant (Fuji Ⅸ GP) or non-fluoride-releasing resin sealant (Concise).After thermocycling for 300 cycles, the surface microhardness of sound enamel 1 mm away from sealant-filled cavities in each group was measured. Then after the treated molars were placed in an artificial demineralizing solution for a week, their surface microhardness was detected again. Results The mean reduct