山梨醇（sorbitol）.docVIP

山梨醇（sorbitol） Sorbitol Encyclopedia Sorbitol was isolated from mountain strawberries by French Boussingault, and hence named sorbitol, and Boye was successfully synthesized in 1958. In 1961, Liaoning Dalian oil chemical plant was put into operation. The current recorded in Australia, Britain, the Czech Republic, and Europe, France and Germany, Hungary, Italy, New Zealand, Portugal, Switzerland and other pharmacopoeia. Brief introduction: Sorbitol Diuretic diuretics. English Name: Sorbitolum EINECS, 200-061-5[1] Alias: D - G1ucitol, Sorbol, Diakarmon, Nivitin Molecular formula: C6H14O6 Properties: white crystalline powder, odorless, slightly sweet, slightly wet. Soluble in water, soluble in ethanol. 5.48% aqueous solution is isotonic solution. Injection system: colorless transparent liquid. Storage: airtight preservation. Preparation: injection: 250mL (containing 62.5g), 100mL (containing 25g), 250mL (containing 50g). Clinical application: Indications: for the treatment of cerebral edema and glaucoma, but also for cardiac and renal function of normal edema, oliguria. Dosage: intravenous drip, once 25% solution, 250 to 500m1, children once 1 to 2g/kg, in 20~30 minutes to enter. To reduce brain edema, repeat the injection every 6~12 hours. Drug analysis: Methods: Determination of sorbitol, sorbitol, the main raw material for sorbitol oxidation reduction titration Application: this method uses titration method to determine the content of sorbitol in Zhongshan pear. The method is applicable to sorbitol raw material medicine. Principle: the sample was diluted with water after the appropriate amount of the iodine bottle, high sodium iodate (potassium) solution and potassium iodide solution, titration with sodium thiosulfate titration solution, near end point, add starch indicator solution and continue the titration to the disappearance of the blue, and the titration correction by blank test results, according to the dosage titration calculation of the content of sorbitol s