亚临床甲状腺功能减退与2型糖尿病慢性并发症的关系.pdfVIP

生垦蕉星疸苤查!!!!生!旦筮；；鲞箜!塑坠i垒』坠!坠!!箜!』!垒!!!z21111y!!：!!!盟Q：! ·25· ·糖尿病临床流行病学· 亚临床甲状腺功能减退与2型糖尿病 慢性并发症的关系 张冬梅张莉 郑莹莹 曾怡廖岚 雷闽湘 【摘要】 目的探讨亚临床甲状腺功能减退(SCH)与T2DM慢性并发症的关系。方法将1294 例T2DM患者分为scH组和甲状腺功能正常组，比较两组间慢性并发症患病率及患者的甲状腺功能，采 用L09istic多元回归分析SCH与T2DM慢性并发症的关系。结果 18．8％的T2DM患者合并sCH。 SCH组糖尿病慢性肾脏疾病(CKD)、DR、糖尿病周围神经病变(DPN)和糖尿病足(DF)患病率均高于甲 Logistic多元回归分析显示，SCH为CKD的独立危险因素(0R一3．39，P—O．012)。结论 T2DM合 并SCH患者Cl(D、DR、DPN和DF患病率升高。SCH是CKD的独立危险因素。 【关键词】糖尿病，2型；糖尿病慢性并发症；亚临床甲状腺功能减退；糖尿病大血管病变 doi：10．3969／i．issn．1006—6187．2014．01．007 A鼹∞iati锄of辄bdinicaI diabeticch瑚lic 2diab“ic hypothyroidism嘲thc蝴lplicatio璐in pati钮b type ZHANG Do孢舭“，ZHANG Li，ZH田＼，GⅥ孢g-yi咒g，甜nz．眈加n打聊￡o厂E竹docri咒ozogy，Xi。规gw H0s夕i纽Z，(、肋￡mfS0“旃阮i粥”泐，饶彻g奶口4j0D08，@i抛 7ro theclinicalcharacteristicsofT2DM withsubclinical 【Abstract】obiectiveinvestigate patients the betweenSCHanddiabeticchronic hypothyroidism(SCH)，andexplorereIationship compIications． MethodsC1iTlicalcharacteristicsand ofdiabeticchr。nic chrollic prevalence camplications，includingkidney disease(CKD)，DR，diabetic diabeticfoot(DF)，、Vere peripheralneuropathy(DPN)and compared between with versussubclinical functionwasalsostudiedin patientseuthyToid hypothyroidism．Thymid withchronic modelswereusedtoestimateassociationof patients complications．Logisticregression subclinical 谢thdiabetic Tk ofsubclinical hypothyroidism complications。R签Illtsprevalence inT2DM with diabetic with hypothyroidisminpatients、^，as18．8％．Comparedeuthyroidpatients，patients subclinical hada ofCKD，DR，DPNandDF(PO．05)．Diabetic