流行病学（英文）.ppt

Case-Control Studies Introduction Matching Investigate Example Design of Case-Control Studies Data collection and analysis Bias Strengths and Weaknesses Several important features Introduction Historical Perspective Definition Types of Design Unique contribution of epidemiology to the repertoire of clinical research designs First case-control study performed in late 1950s Doll and Hill’s study of lung cancer and smoking behavior among physicians Jerome Cornfield’s classic description of “Retrospective Studies” New statistical tools were developed to analyze the study design - logistic regressi