顺式阿曲库铵在肾拟移植手术麻醉中应用的临床研究.pdfVIP

昆 明医学院学报 2010 ，（7）：124～ 126 CN 53 - 1049/ R Journal of Kunming Medical University 顺式阿曲库铵在肾移植手术麻醉中应用的临床研究 谢先丰，杨孟昌，兰志勋 （四川省医学科学院·四川省人民医院麻醉科，四川成都 610072） ［摘要］目的 观察顺式阿曲库铵在肾移植手术麻醉中应用时的肌松作用与安全性．方法 22 例肾功能衰 竭接受肾移植手术的患者为实验组，22 例肾功能正常接受普外手术的患者为对照组．两组患者均采用相同方法 诱导与维持，TOF- WATCH 作肌松监测．结果 顺式阿曲库铵的肌松作用和对生命体征的影响在两组患者之间 无统计学差异（P ＞0.05）．结论 顺式阿曲库铵可以安全有效地用于肾移植手术时的麻醉． ［关键词］顺式阿曲库铵；肾移植；麻醉 + ［中图分类号］R971 .2 ［文献标识码］A ［文章编号］1003－4706 （2010）07 －0124 －03 Clinical Observat ion of Cisat racurium in Pat ient s Undergoing Renal Transplant ion XIE Xian －feng，YANG Meng－chang，LAN Zhi －xun （Dept. of Anesthesiology ，Sichuan Academy of Medical Science Sichuan Provincial People ’s Hospital ， Chengdu Sichuan 610072，China） ［Abstract］ Objective To observe the muscle relaxing effect and safety of cisatracurium in patients undergoing renal transplantion ．Methods 22 patients with renal failure who undergoing renal transplantion were selected into experimental group，and 22 patients undergoing abdominal surgery were selected into the control group ．The same way of anesthesia induction and maintain was used in patients in the two groups ．The TOF mode of stimulation was used to monitor muscle relax of patients ．Result There was no statistically significant difference in the muscle relaxing effect and the effect of cisatracurium on vital signs of patients between the two groups （P ＞0.05）．Conclusion Cisatracurium can be safely and effectively used in patients undergoing renal transplantion. ［Key words］Cisatracurium；Renal transplantion ；Anesthesia 顺式阿曲库铵是一种新型中时效非去极化肌 竭患者的麻醉．国产顺式阿曲库铵（商品名库泰 松剂，它是阿曲库铵十种同分异构体中的一种， 东英药业）是拥有国内自主产权的顺式阿曲库铵 为顺式旋光异构体，通过与运动终板胆碱