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Neuroradiology (2016) 58:979–985
DOI 10.1007/s00234-016-1729-3
DIAGNOSTIC NEURORADIOLOGY
Wall enhancement on high-resolution magnetic resonance
imaging may predict an unsteady state of an intracranial saccular
aneurysm
Peng Hu 1 Qi Yang2 Dan-Dan Wang 3 Shao-Chen Guan4 Hong-Qi Zhang 1
Received: 16 May 2016 /Accepted: 8 July 2016 /Published online: 20 July 2016
# Springer-Verlag Berlin Heidelberg 2016
Abstract investigations and clinical courses. The statistical analysis indi-
Introduction The aneurysm wall has been reported to play a cated no significant correlation between aneurysm wall en-
critical role in the formation, development, and even rupture hancement and aneurysm size. However, there was a strong
of an aneurysm. We used high-resolution magnetic resonance correlation between wall enhancement and aneurysm symp-
imaging (HRMRI) to investigate the aneurysm wall in an ef- toms, with a kappa value of 0.86 (95 % CI 0.68– 1).
fort to identify evidence of inflammation invasion and define Conclusions Aneurysm wall enhancement on HRMRI might
its relationship with aneurysm behavior. be a sign of inflammatory change. Symptomatic aneurysms
Methods Patients with intracranial aneurysms who were pro- exhibited wall enhancement on HRMRI. Wall enhancement
spectively evaluated using HRMRI between July 2013 and had a high consistent correlation of symptomatic aneurysms.
June 2014 were enrolled in this study. The aneurysm’s wall Therefore, wall enhancement on HRMRI might predict an
enhancement and evidence of inflammation invasion were unsteady state of an intracranial saccular aneurysm.
determined. In addition, the relationship between aneurysm
wall enhancement and aneurysm size and symptoms, includ-
ing ruptured aneurysms, giant unrupu
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