MR医学影像文献Li-2016-Brain tumor segmentation from multimod.pdfVIP

Artificial Intelligence in Medicine 73 (2016) 1–13 Contents lists available at ScienceDirect Artificial Intelligence in Medicine j o u r n a l h o me p ag e: w w w. elsev /locate/aiim Brain tumor segmentation from multimodal magnetic resonance images via sparse representation Yuhong Li a , Fucang Jia a,∗ , Jing Qin b a Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China b The Centrefor Smart Health, School of Nursing, The Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Kowloon, Hong Kong, China a r t i c l e i n f o a b s t r a c t Article history: Objective: Accurately segmenting and quantifying brain gliomas from magnetic resonance (MR) images Received 23 March 2016 remains a challenging task because of the large spatial and structural variability among brain tumors. To Received in revised form 24 July 2016 develop a fully automatic and accurate brain tumor segmentation algorithm, we present a probabilistic Accepted 30 August 2016 model of multimodal MR brain tumor segmentation. This model combines sparse representation and the Markov random field (MRF) to solve the spatial and structural variability problem. Keywords: Methods: We formulate the tumor segmentation problem as a multi-classification task by labeling each Sparse representation voxel as the maximum posterior probability. We estimate the maximu