烧伤患者感染病原菌及耐药性分析-中南大学学报医学版.pdfVIP

BU LL HUNAN MED UNIV 2003, 28( 4) 405 张 曦, 赵柏程 ( 中南大学湘雅二医院烧伤科, 长沙410011) [ ] 目的: 了解烧伤患者感染病原菌和细菌耐药性变迁方法: 分别对 1991 年7 ~ 1996 年 6 和 1996 年7 ~ 200 1 年 6 两 个时期烧伤病人的血及创面培养的细菌检出情况及药物敏感性进行调查结果: 革 兰阴性菌是主要的烧伤感染菌, 铜绿假单胞菌居第一位, 但近五年所占百分比有所下降; 革兰阳性菌中金黄色葡 萄球菌居第一位, 后五年较前五年有所上升, 其中耐甲氧西林金黄色葡萄球菌检出率有较大程度上升; 阴沟肠杆 菌( 10. 4% ) 大肠埃希菌( 8. 3% ) 肺炎克雷伯菌( 7. 3% ) 真菌( 4. 2% ) 检出率有一定程度的上升; 金黄色葡萄球 菌, 铜绿假单胞菌等的耐药菌株有明显上升趋势结论: 烧伤感染病原菌和细菌耐药性变迁与头孢他啶亚胺培 南等广谱抗生素广泛应用可能有一定关系; 不间断地监测烧伤感染菌种及耐药性变化, 可为本病区防治感染提供 有意义的参考资料 [ ] 烧伤; 感染; 细菌; 微生物敏感性试验 [ ] R644; R446. 5 [ ] A [ ] 2003) Inf ective pathogens and drug resistance i n burned patients ZHANG Xi , ZHAO Bo heng ( Dep ar tment of Bur n, Second Xiangya H osp ital , Central South Univ ersity , Changsha 410011, China) Abstract: Objective To find out the hanges in the infe tive pathogens and their drug resis tan e in burned patients. Methods The patients were divided into tw o groups. The first group w as from July 199 1 to June 1996, and the se ond group w as from July 1996 to June 2001. The ba teria of burned body surfa e and blood w ere ultured, and the ba teria and their drug sensitivity were ana lyzed. Results Gramnegative ba teria w ere the major ba teria in burn infe tion, among w hi h Pseudomonas aer uginosa ranked the top. Stap hylococcus aureous ranked the first among the Gram positive ba teria, and the isolation rate of methi illin resistant S tap hylococcus aureus in reased; T he isolation rate of E ntero acter cloacae ( 10. 4% ) , Escher ichia coli ( 8. 3%) , K le siella p neumoniae (7. 3%) , and fungus ( 4. 2% ) all rose. T he antibioti resistant strains of