尿毒症期肾移植受者术前血栓弹力图检测结果分析.pdfVIP

·14 · 解放军医药杂志2015年7月 第27卷 第7期 Med PharmJ Chin PLA,Vol.27,No.7,Jul.2015 ·论著 · 尿毒症期肾移植受者术前血栓弹力图检测结果分析 孟祥红,李　 钢 　 　 [摘要]　 目的　 探讨血栓弹力图(TEG)在尿毒症期肾移植患者术前检测凝血功能中的意义。 方法　 对2014 年 6—12月收治的尿毒症期肾移植受者126例(观察组)进行术前TEG检测,选择同期健康体检者(对照组)56例进行比 较,分析尿毒症期肾移植患者术前凝血状况。 结果　 观察组TEG的R值、K值均较对照组明显降低,α值较对照组明 显增加(P0．05),MA值两组比较差异无统计学意义(P 0．05)。 观察组血小板计数少于对照组,活化部分凝血激 酶时间短于对照组,MA值异常率高于对照组(P 0．05)。 结论　 尿毒症期肾移植患者术前凝血功能紊乱且多变, TEG检测能较全面地反映凝血功能,为临床治疗和输血提供参考依据。 　 　 [关键词]　 尿毒症;肾移植;血栓弹力描记术;凝血功能 [中国图书资料分类号]　 R692.5　 　 [文献标志码]　 A　 　 [文章编号]　 2095-140X(2015)07-0014-03 [DOI]　 10.3969/ j.issn.2095-140X.2015.07.004 Results of Thrombelastogram in Detection of Preoperative Renal Transplantation Receptors with Uremia a b MENGXiang-hong ,LI Gang (a. Department of BloodTransfusion,b. Second Department of Urology,309 Hospital of PLA,Beijing 100091,China) [Abstract]　 Objective　 To investigate the significance of thrombelastography (TEG)in detectionof preoperative coagulationfunction of renal transplantationreceptorswithuremia. Methods　 Atotalof 126 renaltransplantationrecep- torswith uremia (observation group)fromJune to December 2014 were detected for preoperative TEG,and56 healthy controlstakingmedicalexaminationsatthesameperiodwerechosenascontrolgroup. Thepreoperativecoagulationcondi- tions of renaltransplantationreceptorswithuremiawereanalyzed. Results　 Comparedwiththoseincontrolgroup,inob- servation group,the RandKvaluesofTEGweresignificantlydecreased,whileαvaluewassignificantlyincreased (P 0．05),and therewas no significant differencein MAvalueinthetwogroups (P0．05). Comparedwiththoseincon- trol group,in observation group,the value of blood platelet count was decreased,and activated partial thromboplastin time (APTT)was shorter,and the abnormal ratio of MA valuewashigher than that in control group (P 0．05). Con- clusion　 Thecoagulationconditionofpreoper