一种用于汞离子选择性检测的新型石墨烯DNA生物传感器.docxVIP

A novel graphene-DNA biosensor for selective detectionof mercury ions一种用于汞离子选择性检测的新型石墨烯DNA生物传感器Abstract摘要A novel electrochemical biosensor for sensitive and selective detection of mercury (II) ions (Hg2+) basedon a DNA grafted graphene is proposed. Graphene oxide (GO) was reduced by dopamine, and then thesingle-strand probe DNA modified at the 5′-end with an alkylamino modifier (NH2-ssDNA) was graftedon the reduced graphene oxide (RGO) surface via Michael addition reaction. In the presence of Hg2+, the target DNA with four thymine–thymine (T–T) mismatches would hybridize with the probe DNA on