建立新诊断理念,服务于临床(2014.4.12乐至会议).ppt [自动保存]课件.ppt

* * * Accuracy makes the difference You need to optimize the diagnosis of C.difficile including toxogenic strains and ensure all true positive patients are accurately detected, thereby contributing to reduced morbidity and lower patient isolation costs. With our gold standard offer combining an automated EIA method (VIDAS) with culture, as recommended by the SHEA (US) and several experts 6,7, we can help you achieve maximum diagnostic * * * * Recall Dennis’ CARD project presentation. He listed these 3 reasons for the project team to be developing new ID cards. I will talk specifically about the first two reasons and how the new developments will impact all of you. * * Comment We must never over sell the benefits of PCT. It is not the perfect bacterial biomarker – but it is the best there is today on the market. It will give false positive and false negative results. Specificity is high but not 100%. Of importance to note is Never test neonates under 2 days old (high PCT and there are no standardized cut-offs) In fact all babies under 2 days will test positive. If in doubt then repeat PCT 6-24 hours in case you have tested PCT too early in the disease course, therefore missing the infection. 胶乳凝集试验 ?肺炎链球菌乳胶凝集试验 ? β-溶血链球菌乳胶凝集试验 ? MRSA乳胶凝集试验 ? 隐球菌荚膜多糖抗原乳胶凝集试验 SLIDEX STREPTO GROUPING KIT 革兰 + 阳性（G+） 触酶 （H2O2）- Slidex Strepto KIT Strepto A Strepto B Strepto C Strepto D Strepto F Strepto G 胶乳凝集试验 阳性凝集 阴性 (positive) (Negitive) MRSA胶乳凝集试验 隐球菌乳胶凝集试验 阴性 阳性 胶乳凝集试验 标本为脑脊液或血清；操作简便、快速，可用于隐球菌感染的早期诊断 灵敏度和特异性均在95%以上，有估计预后和疗效的作用。 隐球菌胶乳凝集试验 显色培养基的应用 –ChromID ESBL鉴定分离超广谱β-内酰胺酶 –Chrom Id Candida分离鉴定念珠菌 –ChromID MRSA 鉴定分离耐甲氧西林金葡菌 –ChromID VRE 鉴定分离万古霉素耐药的肠球菌 显色培养基的应用 多重耐药菌主动筛查与去污染（尤其是ICU病人） 鼻拭子 —MRSA 肛拭子 —ESBLs —VRE —鲍曼不动杆菌 —铜绿假单胞菌 * 产超广谱酶 :大肠：红色; 肺炎克雷伯 菌：绿色; 变形杆菌:棕色 显色培养基的应用 MRSA: 绿色 VRE粪肠球菌:紫色 屎肠球菌:蓝绿色 显色培养基的应用 白色念珠菌: 蓝绿色 显色培养基的应