基于因子分析的早期糖尿病肾病证候要素研究-环球中医药.pdfVIP

环球中医药2016年2月第9卷第2期摇 Global Traditional Chinese Medicine,February2016,Vol郾9,No郾2 摇摇 129 ·论著 · 基于因子分析的早期糖尿病肾病 证候要素研究 申子龙摇 赵进喜摇 王颖辉摇 庞博 揖摘要铱摇 目的摇 研究早期糖尿病肾病患者中医症状、舌脉象及证候要素特征。方法摇 收集 158 例早期糖尿病肾病患者的症状、体征等资料,建立临床数据库,应用因子分析的方法进行统计分析, 并结合临床知识确定中医证候要素。结果摇 因子分析共提取12个公因子,累计贡献率为74.332%, 结合中医证候学进行判断,可归纳为阳虚证、血虚生风证、气虚证、气虚血瘀证、血虚夹瘀证、湿邪内 蕴证、气阴两虚证、阴虚证、痰邪内阻证。结论摇 早期糖尿病肾病证素不外乎虚实两端,治疗应在益 气、养血、养阴、温阳、活血、除湿、化痰的基础上,重视祛风治法。 揖关键词铱摇 糖尿病肾病;摇 因子分析;摇 证素 揖中图分类号铱摇 R259摇 揖文献标识码铱摇 A摇 doi:10郾3969/ j郾issn郾1674鄄1749郾2016郾02郾001 Study on the syndrome characteristics of early diabetic nephropathy based on the factor analysis摇 SHENZi鄄long,ZHAOJin鄄xi,WANGYing鄄hui,etal.摇 DongzhimenHospitalAffiliatedtoBeijing University of Chinese Medicine,Beijing 100700,China Corresponding author:ZHAOJin鄄xi,E鄄mail:zhaojinximd@126.com 揖Abstract铱摇 Objective摇 Study onthecharacteristicsofTCMsymptoms,conditionof thetongueand pulse and syndrome factors of patients with early diabetic nephropathy.Methods摇 The symptoms,signs and other data of 158 patients with early diabetic nephropathy was collected. Clinical database was established and factor analysis method was used for statistical analysis. Results摇 12 kinds of common factorswere obtained and the accumulative contribution rate was74.332%. The most common syndromes were yang deficiency syndrome,windsyndromecausedbyblood鄄deficiency ,qideficiencysyndromeandso on. Conclusion摇 We should pay attention to dispelling wind鄄evil on the basis ofbenefiting qi and nourishing blood,nourishing yin and warming鄄yang,activating blood and drying the wetness鄄evil, eliminating phlegm in the early diabetic nephropathy. 揖Key words铱摇 Diabetic nephropathy;摇 Factor analysis;摇 Syndromefactor 摇 摇 糖尿病肾病( diabetic nephropathy,DN) 是糖尿 范畴,其相关表现与中医古籍记载“肾消冶 “水肿冶 病严重的微血管病变之一,是目前引起终末期肾脏病 “尿浊冶等相关,中医关于早期DN的治疗有几千年的 [1]